Misuse of alprazolam, also known as Xanax, a popular sedative, continues to send tens of thousands of people to the emergency room, according to a new report. The report, which was issued recently by the Substance Abuse and Mental Health Services Administration (SAMHSA), indicates that the number of emergency room visits for non-medical use of the drug doubled between 2005 and 2010.

According to the report, the number of visits in 2005 was 57,419, while the number of visits in 2010 was 124,902. However, the number of visits remained stable at 123,744 in 2011.

Using the drug for non-medical purposes may lead to physical dependence, with withdrawal symptoms such as seizures and tremors. When combined with alcohol or drugs that depress the nervous system, including narcotic pain relievers, the effects of alprazolam on the body could be dangerously enhanced.

According to the National Institutes of Health, alprazolam is used to treat anxiety and panic disorders and works by decreasing abnormal excitement in the brain. This medication may also be used to treat depression, fear of open spaces, and premenstrual syndrome.

The drug, which is also known as Xanax XR and Niravam, was the 13th most frequently sold medication in 2012, and was the most commonly prescribed psychiatric medication in 2011.

Pamela S. Hyde, SAMHSA Administrator, said in a statement, “When used as directed, alprazolam is safe and effective, but misuse can result in serious health consequences.” She continued, “This report highlights the need to educate people about the dangers of misusing or sharing prescription medications and the importance of properly disposing of unused medication.”