Television’s longest-running sitcom Two and a Half Men has finally run out of life. Network president Nina Tassler announced that next year’s twelfth season would be the show’s last before the CBS Upfront presentation on Wednesday.

A perennial high performer in the ratings, the show originally focused on the relationship of two extremely different brothers, played by Jon Cryer and Charlie Sheen, who became unlikely roommates along with Cryer’s character’s young son, played by Angus T. Jones.

Despite commanding an impressive salary, Charlie Sheen was fired from his contract in March of 2011 after a public meltdown that included multiple negative comments about the show. Two and a Half Men carried on, replacing Sheen’s character with a new one played by Ashton Kutcher beginning in the 2011 fall season.

Creator Chuck Lorre reports that the show will go out with a bang. During the upfront announcement, Tassler promised that Lorre was planning a season-long send-off in part inspired by the recently concluded last season of another CBS sitcom, How I met your mother. According to Hollywood Life, Tassler admitted that Lorre had “great ideas and very big surprises,” but declined to comment if a return cameo by Charlie Sheen would be one of them.