Drew Barrymore has been famous from the moment she was born. The actress comes from a long line of well-known Barrymore stage and screen actors. In fact, Barrymore had already starred in her very first commercial by 11 months of age and was only seven years old when Steven Spielberg called her a “natural ham” after working with her on the set of E.T. Flash forward a few decades and Barrymore is an accomplished actress and a major box office attraction.

Speaking at Lucky‘s Fashion and Beauty Blog Conference Thursday in Los Angeles, Barrymore discussed what it’s like to be a working mom (her only child, daughter Olive Barrymore Kopelman, was born in September 2012). Though she’s done almost everything in her career, including acting, directing, attending rehab before finishing high school and flashing “Late Night” host David Letterman, Barrymore says she still can’t do it all.

“I can’t and I don’t,” the actress said at the conference, according to People Magazine. “It sucks,” she added. However, the first-time mother knows that sometimes you’ve got to pass on certain opportunities so that you can spend time with your child or your significant other.

According to Barrymore, she’s unable to direct at the moment because she’d miss out on watching her daughter grow up. Though the choice was a difficult one, she told the conference that it was a clear choice.

Barrymore noted that she was taught growing up that women can have it all. For someone who’s juggling a number of different projects, something has to give and when it does, Barrymore argued that what you choose to stay with eventually gets more of your attention and flourishes.

Though Barrymore contends that you can’t do it all, trying to do some part of what you want to do is good for your psyche, according to a study by the American Psychological Association of over 1,300 moms. The study found that the happiest moms are those who work part-time. The study also discovered that both part- and full-time workers reported fewer symptoms of depression than stay-at-home moms.

For someone like Drew, who had already been attended several drug treatment programs by the age of 13, finding the right balance between work and her home life is important. Here’s to hoping that Barrymore will always find time for acting and for spending time with Olivia.

Do you agree with Barrymore? Can women have it all? How can a working mother juggle both her career and her role as caretaker? Share your thoughts in the comments section.